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Article

PMEL is involved in snake colour pattern transition from blotches to stripes.

Nature communications - 3 Sept 2024

Tzika Athanasia C, Ullate-Agote Asier, Helleboid Pierre-Yves, Kummrow Maya

Abstract excerpt

Corn snakes are emerging models for animal colouration studies. Here, we focus on the Terrazzo morph, whose skin pattern is characterized by stripes rather than blotches. Using genome mapping, we discover a disruptive mutation in the coding region of the Premelanosome protein (PMEL) gene. Our transcriptomic analyses reveal that PMEL expression is significantly downregulated in Terrazzo embryonic tissues. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39227572
DOI: 10.1038/s41467-024-51927-0
PMCID: PMC11371805

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