Article
Fetal microchimerism cells suppress arthritis progression by inducing CD14+ IL-10+ cells in pregnant experimental mice.
International journal of rheumatic diseases - 1 Sept 2024
Chang Da-Wei, Wu Cheng-Chi, Liu Fei-Lan, Lu Chun-Chi, Chu Chen-Chih, Chang Deh-Ming
Abstract excerpt
BACKGROUND: Fetal microchimerism occurs in the mother after a pregnancy. To investigate the role of fetal microchimerism cells (FMCs) in rheumatoid arthritis, we analyzed the population of fetal cells in pregnant experimental arthritis mice. METHODS: We used EGFP+ fetuses, which were mated with either healthy female mice or CIA mice, and male C57BL/6J-Tg (Pgk1-EGFP)03Narl mice, to detect the population of FMCs in...
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