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Magnetic Resonance Imaging Features of Sporadic Optic Chiasmatic-Hypothalamic Gliomas and Correlation with Histopathology and BRAF Gene Alterations.

Neurology India - 1 Jul 2024

Vaidya Tanvi, Sahu Arpita, Epari Sridhar, Shetty Omshree, Gurav Mamta, Sahay Ayushi, Lad Shraddha, Kurki Vineeth, Kapadia Tejas, Chinnaswamy Girish, Goda Jayant, Shetty Prakash, Krishnatry Rahul, Chatterjee Abhishek, Singh Vikas, Moiyadi Aliasgar, Gupta Tejpal

Abstract excerpt

OBJECTIVE: Sporadic optic chiasmatic-hypothalamic gliomas (OCHGs), though histologically low-grade tumors, manifest as aggressive neoplasms radiologically, leading to difficulty in diagnosis. Molecular alterations of the BRAF gene are detectable in a majority of sporadic OCHGs. The purpose of our study was to elucidate the characteristic imaging features of sporadic OCHGs and to investigate whether imaging...

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PMID: 39216028
DOI: 10.4103/neurol-india.ni_521_22

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BRAF

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