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Article

An ensemble approach for circular RNA-disease association prediction using variational autoencoder and genetic algorithm.

Journal of bioinformatics and computational biology - 1 Aug 2024

Salooja C M, Sanker Arjun, Deepthi K, Jereesh A S

Abstract excerpt

Circular RNAs (circRNAs) are endogenous non-coding RNAs with a covalently closed loop structure. They have many biological functions, mainly regulatory ones. They have been proven to modulate protein-coding genes in the human genome. CircRNAs are linked to various diseases like Alzheimer's disease, diabetes, atherosclerosis, Parkinson's disease and cancer. Identifying the associations between circular RNAs and...

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PMID: 39215523
DOI: 10.1142/S0219720024500185

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