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Article

Emerging Therapeutic Approaches and Genetic Insights in Stargardt Disease: A Comprehensive Review.

International journal of molecular sciences - 14 Aug 2024

Ghenciu Laura Andreea, Hațegan Ovidiu Alin, Stoicescu Emil Robert, Iacob Roxana, Șișu Alina Maria

Abstract excerpt

Stargardt disease, one of the most common forms of inherited retinal diseases, affects individuals worldwide. The primary cause is mutations in the ABCA4 gene, leading to the accumulation of toxic byproducts in the retinal pigment epithelium (RPE) and subsequent photoreceptor cell degeneration. Over the past few years, research on Stargardt disease has advanced significantly, focusing on clinical and molecular...

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Source

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Identifiers

PMID: 39201545
DOI: 10.3390/ijms25168859
PMCID: PMC11354485

Genes

ABCA4
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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