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Article

Current landscape of fertility induction in males with congenital hypogonadotropic hypogonadism

27 Aug 2024

Abstract excerpt

Congenital hypogonadotropic hypogonadism (CHH) is a rare reproductive disorder caused by deficient secretion or action of gonadotropin-releasing hormone (GnRH) and is a hormonally treatable form of male infertility. Both pulsatile GnRH treatment and combined gonadotropin therapy effectively induce spermatogenesis in 75%-80% of males with CHH, albeit the ejaculate does not usually approach normal semen parameters...

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PMID: 39190467
DOI: 10.1111/nyas.15214

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