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A Negative Feedback Loop Compromises NMD‐Mediated Virus Restriction by the Autophagy Pathway in Plants

21 Jun 2024

Abstract excerpt

Nonsense-mediated decay (NMD) and autophagy play pivotal roles in restricting virus infection in plants. However, the interconnection between these two pathways in viral infections has not been explored. Here, it is shown that overexpression of NbSMG7 and NbUPF3 attenuates cucumber green mottle mosaic virus (CGMMV) infection by recognizing the viral internal termination codon and vice versa. NbSMG7 is subjected...

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PMID: 39189522
DOI: 10.1002/advs.202400978

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