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Development of RPA-Cas12a assay for rapid and sensitive detection of Pneumocystis jirovecii

26 Aug 2024

Abstract excerpt

Pneumocystis jirovecii is a prevalent opportunistic fungal pathogen that can lead to life-threatening Pneumocystis pneumonia in immunocompromised individuals. Given that timely and accurate diagnosis is essential for initiating prompt treatment and enhancing patient outcomes, it is vital to develop a rapid, simple, and sensitive method for P. jirovecii detection. Herein, we exploited a novel detection method for...

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PMID: 39187803
DOI: 10.1186/s12866-024-03440-z

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