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Anti-Purkinje Cell Cytoplasmic Antibody Type 2-Associated Autoimmune Cerebellar Degeneration in Children: A Different Phenotype From Adults.

Pediatric neurology - 1 Nov 2024

Zhou Anna, Ren Haitao, Fu Libing, Ren Changhong, Zhou Ji, Guan Hongzhi, Ren Xiaotun, Zhang Weihua

Abstract excerpt

BACKGROUND: Anti-Purkinje cell cytoplasmic antibody type 2 (PCA-2) is associated with various neurological conditions in adults. However, related studies have not been conducted in children. The present study aimed to characterize the clinical features and outcomes of PCA-2-related autoimmune cerebellar degeneration in pediatric patients. METHODS: A total of 357 pediatric patients with acute or subacute...

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PMID: 39178650
DOI: 10.1016/j.pediatrneurol.2024.07.004

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