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Resolved genomes of wastewater ESBL-producing Escherichia coli and metagenomic analysis of source wastewater samples

22 Aug 2024

Abstract excerpt

ABSTRACT Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli pose a serious threat to human health because of their resistance to the most commonly prescribed antibiotics: penicillins and cephalosporins. In this study, we provide a genomic and metagenomic context for the determinant beta-lactam resistance genes of ESBL-positive E. coli isolated from various wastewater treatment utilities in Oregon,...

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PMID: 39166863
DOI: 10.1128/spectrum.00717-24

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