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Phenotypic and genomic analysis of the hypervirulent methicillin-resistant Staphylococcus aureus ST630 clone in China.

mSystems - 17 Sept 2024

Shi Junhong, Xiao Yanghua, Shen Li, Wan Cailing, Wang Bingjie, Zhou Peiyao, Zhang Jiao, Han Weihua, Yu Fangyou

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA) sequence type 630 (ST630) is a rarely reported lineage worldwide. This study aimed to trace the dissemination of the emerging MRSA ST630 clones in China and investigate their virulence potential. We collected 22 ST630-MRSA isolates from across China and performed whole-genome sequencing analysis and virulence characterization on these isolates. Epidemiological...

Topics

Methicillin-Resistant Staphylococcus aureus
China
Humans
Animals
Staphylococcal Infections
Virulence
Mice
Phylogeny
Phenotype
Whole Genome Sequencing
Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Male

Virulence Factors

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Open in PubMed Open full text

Identifiers

PMID: 39158330
DOI: 10.1128/msystems.00664-24
PMCID: PMC11406941

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