Article
BioM2: biologically informed multi-stage machine learning for phenotype prediction using omics data.
Briefings in bioinformatics - 25 Jul 2024
Zhang Shunjie, Li Pan, Wang Shenghan, Zhu Jijun, Huang Zhongting, Cai Fuqiang, Freidel Sebastian, Ling Fei, Schwarz Emanuel, Chen Junfang
Abstract excerpt
Navigating the complex landscape of high-dimensional omics data with machine learning models presents a significant challenge. The integration of biological domain knowledge into these models has shown promise in creating more meaningful stratifications of predictor variables, leading to algorithms that are both more accurate and generalizable. However, the wider availability of machine learning tools capable of...
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