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Naturally occurring horse model of miscarriage reveals temporal relationship between chromosomal aberration type and point of lethality

5 Aug 2024

Abstract excerpt

Chromosomal abnormalities are a common cause of human miscarriage but rarely reported in any other species. As a result, there are currently inadequate animal models available to study this condition. Horses present one potential model since mares receive intense gynecological care. This allowed us to investigate the prevalence of chromosomal copy number aberrations in 256 products of conception (POC) in a...

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PMID: 39102548
DOI: 10.1073/pnas.2405636121

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