Article
Congenital dysfibrinogenemias. A review.
La Ricerca in clinica e in laboratorio - 1 Jan 2000
Rocha E, Páramo J A, Aranda A, Cuesta B, Fernández J
Abstract excerpt
Inherited qualitative abnormalities of fibrinogen have been documented in 144 families. These dysfibrinogenemias have been inherited as autosomal dominant traits and usually are clinically silent, but in some cases are associated with bleeding, thrombosis, or defective wound healing. Dysfibrinogenemias may be associated with defects in any of the three basic steps in the thrombin-fibrinogen reaction, i.e.,...
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