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Prevalence and potential impact of human pegivirus-1 on HIV-1 disease progression among Indian PLHIV.

Journal of infection in developing countries - 29 Jul 2024

Alex Diviya, Steve Runal J, Ramalingam Veena V, Demosthenes John P, Vijayalakshmi Gopinathan, Ghale Ben C, Rupali Priscilla, Varghese George M, Daniel Dolly, Rebekah Grace, Fletcher Gnanadurai J, Abraham Priya, Kannangai Rajesh

Abstract excerpt

INTRODUCTION: Human pegivirus-1 (HPgV-1) influences the pathogenesis and outcome of viral infections. We investigated the prevalence and impact of HPgV-1 due to the paucity of studies on Indian people living with HIV (PLHIV). METHODOLOGY: Samples were collected from 347 treatment-naïve PLHIV; and 100 blood donors negative for HIV, HBV, and HCV. CD4+ T-cell and HIV-1 viral load were measured using flow-cytometry...

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CD4 Lymphocyte Count
Coinfection
Flaviviridae Infections
HIV-1
HIV Infections

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PMID: 39078797
DOI: 10.3855/jidc.19397

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