Article
Aspartate aminotransferase of Rhizobium leguminosarum has extended substrate specificity and metabolizes aspartate to enable N2 fixation in pea nodules.
Microbiology (Reading, England) - 1 Jul 2024
Ledermann Raphael, Bourdès Alexandre, Schuller Marion, Jorrin Beatriz, Ahel Ivan, Poole Philip Simon
Abstract excerpt
Rhizobium leguminosarum aspartate aminotransferase (AatA) mutants show drastically reduced symbiotic nitrogen fixation in legume nodules. Whilst AatA reversibly transaminates the two major amino-donor compounds aspartate and glutamate, the reason for the lack of N2 fixation in the mutant has remained unclear. During our investigations into the role of AatA, we found that it catalyses an additional transamination...
Topics
- Rhizobium leguminosarum
- Aspartic Acid
- Pisum sativum
- Root Nodules, Plant
- Nitrogen Fixation
- Aspartate Aminotransferases
- Substrate Specificity
- Bacterial Proteins
- Symbiosis
- Mutation