Article
Predictive value of CXCL1+_FAP+ phenotype in CAFs for distant metastasis and its correlation with PD-L1 expression in locoregionally advanced nasopharyngeal carcinoma patients.
Oral oncology - 1 Oct 2024
Wen Yue-Feng, Huang Wen-Jin, Chen Xiao-Long, Cai Hui-Tang, Zhang Yi-Bin, Song Xian-Lu, Xie Chang-Bin, Peng Hai-Hua, Yu Hong-Wei, Chen Cheng-Cong, Wei Li-Qiu, Zhou Tong-Chong, Cai Shuang, Wang Fang, Lin Xiao-Dan
Abstract excerpt
OBJECTIVE: There is a lack of effective biomarkers for predicting the distant metastasis in nasopharyngeal carcinoma (NPC). We aimed to explore the expression of FAP+Cancer-associated fibroblasts (CAFs) derived CXCL1 in NPC and its predictive values for distant metastasis and correlation with PD-L1 expression. MATERIALS AND METHODS: A total of 345 patients with locoregionally advanced NPC were retrospectively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.