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A case of hepatoid adenocarcinoma of the lung harboring KRAS G12C responded favorably to sotorasib.

Pathology international - 1 Sept 2024

Uruga Hironori, Miyamoto Atsushi, Fujii Takeshi, Okuma Takashi, Mitsumura Takahiro, Tamaoka Meiyo, Takazawa Yutaka

Abstract excerpt

Hepatoid adenocarcinoma of the lung is a rare variant of adenocarcinoma. We describe a case of hepatoid adenocarcinoma of the lung that harbored KRAS G12C and responded favorably to sotorasib. A man in his 70s was found to have an abnormality on his chest X-ray. He underwent right middle lobectomy, and a pathological examination of the surgical specimen showed conventional invasive adenocarcinoma with highly...

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PMID: 39016668
DOI: 10.1111/pin.13464

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A case of hepatoid adenocarcinoma of the lung harboring KRAS G12C responded favorably to sotorasib.PMID 39016668Read ↗

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Incidence of Brain Metastases and Preliminary Evidence of Intracranial Activity With Sotorasib in Patients With KRASG12C-Mutant Non–Small-Cell Lung CancerSemantic proximity Read ↗

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