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Early mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants in Chile.

Scientific reports - 11 Jul 2024

Oróstica Karen Y, Mohr Sebastian B, Dehning Jonas, Bauer Simon, Medina-Ortiz David, Iftekhar Emil N, Mujica Karen, Covarrubias Paulo C, Ulloa Soledad, Castillo Andrés E, Daza-Sánchez Anamaría, Verdugo Ricardo A, Fernández Jorge, Olivera-Nappa Álvaro, Priesemann Viola, Contreras Seba

Abstract excerpt

Genomic surveillance (GS) programmes were crucial in identifying and quantifying the mutating patterns of SARS-CoV-2 during the COVID-19 pandemic. In this work, we develop a Bayesian framework to quantify the relative transmissibility of different variants tailored for regions with limited GS. We use it to study the relative transmissibility of SARS-CoV-2 variants in Chile. Among the 3443 SARS-CoV-2 genomes...

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Identifiers

PMID: 38987406
DOI: 10.1038/s41598-024-66885-2
PMCID: PMC11237036

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