Article
Body-wide chimerism and mosaicism are predominant causes of naturally occurring ABO discrepancies.
British journal of haematology - 1 Sept 2024
Dauber Eva-Maria, Haas Oskar A, Nebral Karin, Gassner Christoph, Haslinger Sabrina, Geyeregger René, Hustinx Hein, Lejon Crottet Sofia, Scharberg Erwin A, Müller-Steinhardt Michael, Schönbacher Marlies, Mayr Wolfgang R, Körmöczi Günther F
Abstract excerpt
Routine ABO blood group typing of apparently healthy individuals sporadically uncovers unexplained mixed-field reactions. Such blood group discrepancies can either result from a haematopoiesis-confined or body-wide dispersed chimerism or mosaicism. Taking the distinct clinical consequences of these four different possibilities into account, we explored the responsible cause in nine affected individuals. Genotype...
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