Article
A Visual Analysis of the Research Dynamics in Resistance to EGFR Inhibitors for NSCLC.
Drug design, development and therapy - 1 Jan 2024
Shao Jun, Gu Yunru, Guo Renhua, Xu Jiali
Abstract excerpt
Purpose: Activating mutations in epidermal growth factor receptor (EGFR) have been identified as key predictive biomarkers for the customized treatment with EGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC), aiding in improving patient response rates and survival. However, resistance challenges the efficacy of these treatments, with limited understanding of post-resistance therapeutic...
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