Article
Phase variable colony variants are conserved across Gardnerella spp. and exhibit different virulence-associated phenotypes.
mSphere - 30 Jul 2024
Garcia Erin M, Klimowicz Amy K, Edupuganti Laahirie, Topf Madeline A, Bhide Shraddha R, Slusser Dawson J, Leib Samantha M, Coddington Cayden L, Matveyev Andrey, Buck Gregory A, Jefferson Kimberly K, Pepperell Caitlin S, Dillard Joseph P
Abstract excerpt
The Gardnerella genus, comprising at least 13 species, is associated with the polymicrobial disorder bacterial vaginosis (BV). However, the details of BV pathogenesis are poorly defined, and the contributions made by individual species, including Gardnerella spp., are largely unknown. We report here that colony phenotypes characterized by size (large and small) and opacity (opaque and translucent) are phase...
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