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Beyond Death: Unmasking the Intricacies of Apoptosis Escape

18 Jun 2024

Abstract excerpt

Apoptosis, or programmed cell death, maintains tissue homeostasis by eliminating damaged or unnecessary cells. However, cells can evade this process, contributing to conditions such as cancer. Escape mechanisms include anoikis, mitochondrial DNA depletion, cellular FLICE inhibitory protein (c-FLIP), endosomal sorting complexes required for transport (ESCRT), mitotic slippage, anastasis, and blebbishield...

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PMID: 38890247
DOI: 10.1007/s40291-024-00718-w

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