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Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight

11 Jun 2024

Abstract excerpt

Spaceflight can change metabolic, immunological, and biological homeostasis and cause skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact of short-duration spaceflight on the skin, we conducted skin biopsies on the Inspiration4 crew members before (L-44) and after (R + 1) flight. Leveraging multi-omics assays including GeoMx™ Digital Spatial Profiler, single-cell...

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PMID: 38862494
DOI: 10.1038/s41467-024-48625-2

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