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The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis

5 Jun 2024

Abstract excerpt

The skin-penetrating gastrointestinal parasitic nematode Strongyloides stercoralis causes strongyloidiasis, which is a neglected tropical disease that is associated with severe chronic illness and fatalities. Unlike other human-infective nematodes, S. stercoralis cycles through a single free-living generation and thus serves as a genetically tractable model organism for understanding the mechanisms that enable...

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PMID: 38839055
DOI: 10.1093/g3journal/jkae122

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