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Evolution of intracytoplasmic sperm injection: From initial challenges to wider applications

1 Jan 2024

Abstract excerpt

Background: In vitro fertilization (IVF) has revolutionized infertility treatment. Nevertheless, male infertility requires more effective solutions. In 1992, the first-ever case of human birth via intracytoplasmic sperm injection (ICSI) was reported. ICSI involves microscopically injecting a sperm into an ovum. Successful ICSI has become a reliable therapy for couples facing infertility, a significant milestone....

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PMID: 38803410
DOI: 10.1002/rmb2.12582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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