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Exploring Gut Microbiome Composition and Circulating Microbial DNA Fragments in Patients with Stage II/III Colorectal Cancer: A Comprehensive Analysis

18 May 2024

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) significantly contributes to cancer-related mortality, necessitating the exploration of prognostic factors beyond TNM staging. This study investigates the composition of the gut microbiome and microbial DNA fragments in stage II/III CRC. METHODS: rRNA sequencing, and blood samples were tested for the presence of microbial DNA fragments. De novo clustering analysis categorized...

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PMID: 38792001
DOI: 10.3390/cancers16101923

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