Article
Real-World Analysis of Post-Progression Treatment Patterns and Outcomes for EGFR Mutation-Positive Patients Treated with First-Line Osimertinib.
Current oncology (Toronto, Ont.) - 26 Apr 2024
Gibson Amanda Jane Williams, Dean Michelle Liane, Litt Ishjot, Box Adrian, Cheung Winson Y, Navani Vishal
Abstract excerpt
Introduction: The use of osimertinib in the first-line (1L) setting is an effective treatment option for sensitizing EGFR-mutations (EGFRm+) and has significantly altered the standard of care practice for EGFRm+ disease in Canada. Unfortunately, acquired resistance to osimertinib is almost universal, and outcomes are disparate. Post-progression treatment patterns and the outcome of real-world Canadian EGFRm+...
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