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Article

Identification of potential therapeutic targets for plaque vulnerability based on an integrated analysis.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jul 2024

Miao Liu, Qin Yue-Ai, Yang Zhi-Jie, Shi Wan-Xin, Wei Xin-Qiao, Liu Yuan, Liu Yan-Li

Abstract excerpt

BACKGROUND AND AIMS: This study aimed to explore potential hub genes and pathways of plaque vulnerability and to investigate possible therapeutic targets for acute coronary syndrome (ACS). METHODS AND RESULTS: Four microarray datasets were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs), weighted gene coexpression networks (WGCNA) and immune cell inﬁltration...

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Topics

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Share to Acute Coronary Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neural Networks, Computer

Share to Plaque, Atherosclerotic

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Share to Rupture, Spontaneous

Source

Identifiers

PMID: 38749785
DOI: 10.1016/j.numecd.2024.02.005

Genes

GZMA
GZMB
CAD
KLRB1
KLRD1
TRPM6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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