Article
Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE.
Analytical cellular pathology (Amsterdam) - 1 Jan 2024
Ding Zhengzheng, Wu Liuxin, Sun Yue, Zhu Yuanyuan, Zuo Qing, Yuan Li, Wang Cong, Sun Lizhou, Xu Yetao, Zhang Yuanyuan
Abstract excerpt
Preeclampsia (PE) manifests as a pregnancy-specific complication arising from compromised placentation characterized by inadequate trophoblast invasion. A growing body of evidence underscores the pivotal involvement of pseudogenes, a subset of long noncoding RNAs, in the pathological processes of PE. This study presents a novel finding, demonstrating a significant downregulation of the pseudogene PDIA3P1 in PE...
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