Impact of root canal disinfection on the bacteriome present in primary endodontic infection: A next generation sequencing study

Abstract excerpt

Abstract Aim To investigate the bacteriome present in teeth with primary endodontic infection (PEI) and apical periodontitis (AP) and to determine quantitatively and qualitatively the impact of chemomechanical preparation (CMP) using 2.5% sodium hypochlorite NAOCl on the bacteriome found in PEI with AP using the Illumina MiSeq platform. Methodology Thirty‐six paired samples from 18 patients were successfully...

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