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Article

Atypical functional connectivity between the amygdala and visual, salience regions in infants with genetic liability for autism.

Cerebral cortex (New York, N.Y. : 1991) - 2 May 2024

Liu Janelle, Girault Jessica B, Nishino Tomoyuki, Shen Mark D, Kim Sun Hyung, Burrows Catherine A, Elison Jed T, Marrus Natasha, Wolff Jason J, Botteron Kelly N, Estes Annette M, Dager Stephen R, Hazlett Heather C, McKinstry Robert C, Schultz Robert T, Snyder Abraham Z, Styner Martin, Zwaigenbaum Lonnie, Pruett John R, Piven Joseph, Gao Wei

Abstract excerpt

The amygdala undergoes a period of overgrowth in the first year of life, resulting in enlarged volume by 12 months in infants later diagnosed with ASD. The overgrowth of the amygdala may have functional consequences during infancy. We investigated whether amygdala connectivity differs in 12-month-olds at high likelihood (HL) for ASD (defined by having an older sibling with autism), compared to those at low...

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Identifiers

PMID: 38696599
DOI: 10.1093/cercor/bhae092
PMCID: PMC11065105

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