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SLC7A11 inhibits ferroptosis and downregulates PD-L1 levels in lung adenocarcinoma

9 Apr 2024

Abstract excerpt

Introduction: Lung adenocarcinoma (LUAD) is a prevalent form of lung cancer originating from lung glandular cells with low survival rates despite recent therapeutic advances due to its diverse and complex nature. Recent evidence suggests a link between ferroptosis and the effectiveness of anti-PD-L1 therapy, with potential synergistic effects. Methods: Our study comprehensively analyzed the expression patterns of...

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PMID: 38655266
DOI: 10.3389/fimmu.2024.1372215

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