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Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages

1 Apr 2024

Abstract excerpt

Tumour immune microenvironment (TIME) plays an indispensable role in tumour progression, and tumour-associated macrophages (TAMs) are the most abundant immune cells in TIME. Non-apoptotic regulated cell death (RCD) can avoid the influence of tumour apoptosis resistance on anti-tumour immune response. Specifically, autophagy, ferroptosis, pyroptosis and necroptosis mediate the crosstalk between TAMs and tumour...

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PMID: 38652105
DOI: 10.1111/jcmm.18348

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