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Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi

10 Apr 2024

Abstract excerpt

Wolbachia, a maternally transmitted symbiotic bacterium of insects, can suppress a variety of human pathogens in mosquitoes, including malaria-causing Plasmodium in the Anopheles vector. However, the mechanistic basis of Wolbachia-mediated Plasmodium suppression in mosquitoes is not well understood. In this study, we compared the midgut and carcass transcriptomes of stably infected Anopheles stephensi with...

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PMID: 38598552
DOI: 10.1371/journal.ppat.1012145

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