Article
Genetic predisposition to childhood obesity does not influence the risk of developing skin cancer in adulthood.
Scientific reports - 3 Apr 2024
Keatley Jay, Law Matthew H, Seviiri Mathias, Olsen Catherine M, Pandeya Nirmala, Ong Jue-Sheng, MacGregor Stuart, Whiteman David C, Dusingize Jean Claude
Abstract excerpt
The relationship between body mass index (BMI) and melanoma and other skin cancers remains unclear. The objective of this study was to employ the Mendelian randomization (MR) approach to evaluate the effects of genetically predicted childhood adiposity on the risk of developing skin cancer later in life. Two-sample MR analyses were conducted using summary data from genome-wide association study (GWAS)...
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