Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innovations in Antifungal Drug Discovery among Cell Envelope Synthesis Enzymes through Structural Insights

22 Feb 2024

Abstract excerpt

Life-threatening systemic fungal infections occur in immunocompromised patients at an alarming rate. Current antifungal therapies face challenges like drug resistance and patient toxicity, emphasizing the need for new treatments. Membrane-bound enzymes account for a large proportion of current and potential antifungal targets, especially ones that contribute to cell wall and cell membrane biosynthesis. Moreover,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Click Chemistry and Applications
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38535180
DOI: 10.3390/jof10030171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innovations in Antifungal Drug Discovery among Cell Envelope Synthesis Enzymes through Structural InsightsPMID 38535180Read ↗

Fungal cell wall biogenesis: structural complexity, regulation and inhibitionSemantic proximity Read ↗

Diversity of Cell Wall Related Proteins in Human Pathogenic FungiSemantic proximity Read ↗

The Fungal Cell Wall: Structure, Biosynthesis, and FunctionSemantic proximity Read ↗

Candida and Candidiasis: The Cell Wall as a Potential Molecular Target for Antifungal TherapySemantic proximity Read ↗

Antibiotics and resistance: the two-sided coin of the mycobacterial cell wallSemantic proximity Read ↗

Cell Wall Integrity Pathway Involved in Morphogenesis, Virulence and Antifungal Susceptibility in Cryptococcus neoformansSemantic proximity Read ↗

Biologically Active Secondary Metabolites from the FungiSemantic proximity Read ↗

Antifungal resistance: Emerging mechanisms and implications (Review)Semantic proximity Read ↗

Fungal Genetics, Genomics, and Secondary Metabolites in Pharmaceutical SciencesSemantic proximity Read ↗

Developing novel antifungals: lessons from G protein-coupled receptorsSemantic proximity Read ↗

Cell Wall Associated Factors of Mycobacterium tuberculosis as Major Virulence Determinants: Current Perspectives in Drugs Discovery and DesignSemantic proximity Read ↗

Strategies for mining fungal natural productsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.