Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Prevalence of Familial Hypercholesterolemia Due to the Founder Effect of the LDLR c.2271del Variant in Communities of Oaxaca, Mexico.

Archives of medical research - 1 Apr 2024

Rodríguez-Gutiérrez Perla Graciela, Hernández-Flores Teresita de Jesús, Zepeda-Olmos Paola Montserrat, Reyes-Rodríguez Christian Daniel, Robles-Espinoza Kiabeth, Solís-Gómez Ulises, González-García Juan Ramón, Magaña-Torres María Teresa

Abstract excerpt

INTRODUCTION: In Mexico, familial hypercholesterolemia (FH) is underdiagnosed, but population screening in small communities where at least one homozygous patient has already been detected results in a useful and inexpensive approach to reduce this problem. Considering that we previously reported nine homozygous cases from the state of Oaxaca, we decided to perform a population screening to identify patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Founder Effect

Share to Hyperlipoproteinemia Type II

Share to Mexico

Share to Phenotype

Share to Prevalence

Share to Receptors, LDL

Source

Identifiers

PMID: 38513336
DOI: 10.1016/j.arcmed.2024.102971

Genes

FH
LDLR
APOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High Prevalence of Familial Hypercholesterolemia Due to the Founder Effect of the LDLR c.2271del Variant in Communities of Oaxaca, Mexico.PMID 38513336Read ↗

Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype.Semantic proximity Read ↗

Preliminary spectrum of genetic variants in familial hypercholesterolemia in Argentina.Semantic proximity Read ↗

Screening of LDLR and APOB gene mutations in Mexican patients with homozygous familial hypercholesterolemia.Semantic proximity Read ↗

LDLR Gene Mutation p.Asp360His and Familial Hypercholesterolemia in a Mexican Community.Semantic proximity Read ↗

The panorama of familial hypercholesterolemia in Latin America: a systematic review.Semantic proximity Read ↗

Diagnostic yield of sequencing familial hypercholesterolemia genes in individuals with primary hypercholesterolemia.Semantic proximity Read ↗

Mutational analysis of a cohort with clinical diagnosis of familial hypercholesterolemia: considerations for genetic diagnosis improvement.Semantic proximity Read ↗

Portuguese Familial Hypercholesterolemia Study: presentation of the study and preliminary results.Semantic proximity Read ↗

Compound Heterozygous Familial Hypercholesterolemia Caused by LDLR Variants.Semantic proximity Read ↗

Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217.Semantic proximity Read ↗

Homozygous familial hypercholesterolemia: the c.1055G>A mutation in the LDLR gene and clinical heterogeneity.Semantic proximity Read ↗

Autosomal recessive hypercholesterolemia in Spain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.