Article
Phenotype prediction from single-cell RNA-seq data using attention-based neural networks.
Bioinformatics (Oxford, England) - 1 Feb 2024
Mao Yuzhen, Lin Yen-Yi, Wong Nelson K Y, Volik Stanislav, Sar Funda, Collins Colin, Ester Martin
Abstract excerpt
MOTIVATION: A patient's disease phenotype can be driven and determined by specific groups of cells whose marker genes are either unknown or can only be detected at late-stage using conventional bulk assays such as RNA-Seq technology. Recent advances in single-cell RNA sequencing (scRNA-seq) enable gene expression profiling in cell-level resolution, and therefore have the potential to identify those cells driving...
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