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Article

Genetic architecture of trait variance in craniofacial morphology.

Genetics - 3 Apr 2024

Andrade Fernando, Howell Lisa, Percival Christopher J, Richtsmeier Joan T, Marcucio Ralph S, Hallgrímsson Benedikt, Cheverud James M

Abstract excerpt

The genetic architecture of trait variance has long been of interest in genetics and evolution. One of the earliest attempts to understand this architecture was presented in Lerner's Genetic Homeostasis (1954). Lerner proposed that heterozygotes should be better able to tolerate environmental perturbations because of functional differences between the alleles at a given locus, with each allele optimal for...

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Identifiers

PMID: 38386896
DOI: 10.1093/genetics/iyae028
PMCID: PMC11090463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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