Article
Relationship in development of malocclusions to polymorphisms of selected vitamin D receptors.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jun 2024
Dominiak Marzena, Leszczyszyn Anna, Łaczmańska Izabela, Machoy Monika, Gerber Hanna, Choukroun Joseph, Gedrange Tomasz, Hnitecka Sylwia
Abstract excerpt
BACKGROUND: The development of malocclusion is related to various factor, many of which are still not fully explained. The steroid hormone, 1,25-dihydroxyvitamin D3, has pleiotropic effects. It plays a key role in skeletal metabolism and the control of cell repair by attaching to the nuclear vitamin D steroid receptor (VDR). This vitamin affects bone turnover through the processes of bone tissue formation and...
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