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Cross talk between the liver microbiome and epigenome in patients with metabolic dysfunction-associated steatotic liver disease

5 Feb 2024

Abstract excerpt

BACKGROUND: The pathogenesis of MASLD (metabolic dysfunction-associated steatotic liver disease), including its severe clinical forms, involves complex processes at all levels of biological organization. This study examined the potential link between the liver microbiome profile and epigenetic factors. METHODS: Liver microbial DNA composition was analysed using high throughput 16S rRNA gene sequencing in 116...

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PMID: 38320344
DOI: 10.1016/j.ebiom.2024.104996

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