Article
The Endocrine Phenotype Induced by Pediatric Adrenocortical Tumors Is Age- and Sex-Dependent.
The Journal of clinical endocrinology and metabolism - 12 Jul 2024
Kunstreich Marina, Dunstheimer Desiree, Mier Pascal, Holterhus Paul-Martin, Wudy Stefan A, Huebner Angela, Redlich Antje, Kuhlen Michaela
Abstract excerpt
CONTEXT: Adrenocortical carcinomas are very rare malignancies in childhood associated with poor outcome in advanced disease. Most adrenocortical tumors (ACT) are functional, causing signs and symptoms of adrenal hormone excess. In most studies, endocrine manifestations were reported 4 to 6 months prior to diagnosis. OBJECTIVE: We sought to extend knowledge on endocrine manifestations with regard to age and sex to...
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