Article
Major Drug Resistance Mutations on Reverse Transcriptase Gene in Human Immunodeficiency Virus Type-1 in Indonesia: A Systematic Review.
Current HIV/AIDS reports - 1 Apr 2024
Nurjannah, Jayanti Sri, Tanoerahardjo Francisca Srioetami, Al Musyahadah Ummu Syauqah, Sukowati Caecilia Hapsari Ceriapuri, Massi Muhammad Nasrum
Abstract excerpt
PURPOSE OF REVIEW: The prevalence of HIV-1 in Indonesia is on a concerning upward trajectory, with a concurrent rise in the development of drug-resistant strains, challenging the efficacy of antiretroviral therapy (ART). Many mutations have been found in the pol gene that makes HIV resistant to ART. We aim to review the major drug resistance mutations (DRMs) of reverse transcriptase (RT) of pol gene in HIV-1...
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