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Article

Genetic epidemiology of thalassemia in couples of childbearing age: over 6 years of a thalassemia intervention project.

Molecular biology reports - 18 Jan 2024

Zheng Xiujie, Bao Yantao, Wu Qunyan, Yao Fang, Su Jindi, Yang Yuankai, Liu Zhiqiang, Duan Shan

Abstract excerpt

BACKGROUND: Shenzhen is one of the most populated metropolises in southern China where thalassemia is highly prevalent. The prevention of thalassemia inheritance is an ambition of child-bearing couples. METHODS AND RESULTS: A total of 22,098 peripheral blood samples were collected from 11,049 potentially at-risk couples of childbearing age from Shenzhen. Thalassemia mutations were determined by PCR-based...

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PMID: 38236368
DOI: 10.1007/s11033-023-09091-z

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