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Article

Genetic variants of ABCC8 and clinical manifestations in eight Chinese children with hyperinsulinemic hypoglycemia.

BMC endocrine disorders - 12 Jan 2024

Chang Guoying, Ying Lingwen, Zhang Qianwen, Feng Biyun, Yao Ruen, Ding Yu, Li Juan, Huang Xiaodong, Shen Yongnian, Yu Tingting, Wang Jian, Wang Xiumin

Abstract excerpt

BACKGROUND: ABCC8 variants can cause hyperinsulinemia by activating or deactivating gene expression. This study used targeted exon sequencing to investigate genetic variants of ABCC8 and the associated phenotypic features in Chinese patients with hyperinsulinemic hypoglycemia (HH). METHODS: We enrolled eight Chinese children with HH and analyzed their clinical characteristics, laboratory results, and genetic...

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Identifiers

PMID: 38212772
DOI: 10.1186/s12902-023-01527-8
PMCID: PMC10785495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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