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Gilbert's syndrome leads to elevated bilirubin after initiation of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis.

Pediatric pulmonology - 1 Apr 2024

Patel Nidhi, Ansar Maria, Pham Anh, Thomsen Kelly, McKinzie Cameron J, Polineni Deepika, Esther Charles R, Brown Rebekah F

Abstract excerpt

Nine people with cystic fibrosis (pwCF) were found to have isolated elevations in serum total bilirubin after starting elexacaftor/tezacaftor/ivacaftor (ETI) that were associated with Gilbert's Syndrome. In longitudinal examination, total bilirubin levels increased substantially after initiation of ETI without elevations in liver transaminases in those with this syndrome. Because elevated bilirubin levels in...

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PMID: 38179880
DOI: 10.1002/ppul.26831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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