Microsporidia persistence in host impairs epithelial barriers and increases chances of inflammatory bowel disease

Abstract excerpt

ABSTRACT Microsporidia are intracellular fungus-like pathogens and the infection symptoms include recurrent diarrhea and systematic inflammations. The major infection route of microsporidia is the digestive tract. Since microsporidia are hard to fully eliminate, the interactions and persistence of the pathogen within epithelium may modulate host susceptibility to digestive disorders. In this study, both in vitro...

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