Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of ITPR1 gene as a novel target for hsa-miR-34b-5p in non-obstructive azoospermia: a Ca2+/apoptosis pathway cross-talk

10 Dec 2023

Abstract excerpt

Abstract MiR-34b-5p has been reported as a non-invasive diagnostic biomarker for infertility. However, no gene targets regulating the mechanism of cation of this miRNA are known. In this study, using gene set enrichment analysis the Inositol 1,4,5-Trisphosphate Receptor Type 1 (ITPR1)gene was identified as the sole target for hsa-miR-34b-5p, and found significantly overexpressed in non-obstructive azoospermia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38072953
DOI: 10.1038/s41598-023-49155-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of ITPR1 gene as a novel target for hsa-miR-34b-5p in non-obstructive azoospermia: a Ca2+/apoptosis pathway cross-talkPMID 38072953Read ↗

Integrative bioinformatics analyses of mitochondrial dysfunction-related genes in human non-obstructive azoospermiaSemantic proximity Read ↗

Screening and identification of critical Genes and Pathways Associated with Oxidative Stress in non-obstructive azoospermia patients: an integrative bioinformatics studySemantic proximity Read ↗

A comparison of the expression patterns and diagnostic capability of the ncRNAs NEAT1 and miR-34a in non-obstructive azoospermia and severe oligospermiaSemantic proximity Read ↗

Identification and Potential Value of Candidate Genes in Patients With Non-obstructive AzoospermiaSemantic proximity Read ↗

Altered G-Protein Transduction Protein Gene Expression in the Testis of Infertile Patients with Nonobstructive AzoospermiaSemantic proximity Read ↗

Integrative bioinformatics approaches for identifying potential biomarkers and pathways involved in non-obstructive azoospermiaSemantic proximity Read ↗

Integrative Bioinformatics Analysis for Identifying the Mitochondrial-Related Gene Signature Associated with Immune Infiltration in Premature Ovarian InsufficiencySemantic proximity Read ↗

New insights into the expression profile of MicroRNA-34c and P53 in infertile men spermatozoa and testicular tissueSemantic proximity Read ↗

Identification of ferroptotic genes and phenotypes in idiopathic nonobstructive azoospermia.Semantic proximity Read ↗

Unveiling the Mitophagy Symphony: Harmonizing Genes for Predictive Precision and Immune Resilience in Recurrent MiscarriageSemantic proximity Read ↗

Dysregulation of apoptotic pathway candidate genes and proteins in infertile azoospermia patientsSemantic proximity Read ↗

Weighted Correlation Gene Network Analysis Reveals New Potential Mechanisms and Biomarkers in Non-obstructive AzoospermiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.