Article
Cold atmospheric plasma sensitizes melanoma cells to targeted therapy agents in vitro.
Journal of biophotonics - 1 Mar 2024
Yan Cong, Zhao Lihong, Zhang Xinyue, Chu Zhaowei, Zhou Tong, Zhang Yanbin, Geng Songmei, Guo Kun
Abstract excerpt
Cold atmospheric plasma (CAP) has been reported to kill melanoma cells in vitro and in vivo. BRAF and MEK inhibitors are targeted therapy agents for advanced melanoma patients with BRAF mutations. However, low overall survival and relapse-free survival are still tough challenges due to drug resistance. In this study, we confirmed that CAP alleviated innate drug resistance and promoted the anti-tumor effect of...
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